Application of WHONET in the Analysis of Pseudomonas aeruginosa Resistance to Imipenem and Meropenem

 WHONET software is a database for analyzing microbiology data, specifically antibiotic resistance patterns. Pseudomonas aeruginosa is a significant agent of nosocomial infections and has been identified as a critical priority by the World Health Organization (WHO). The aim of this study was to monitor the resistance patterns of imipenem and meropenem over one year (February 2022-February 2023) using WHONET software 2022.

 A total of 95 P. aeruginosa isolates were obtained from Kowsar Hospital in Sanandaj, Iran. After verification through biochemical tests and 16sRNA PCR, an antibiogram test was performed for each isolate based on The Clinical & Laboratory Standards Institute (CLSI) guidelines. Data were analyzed using WHONET 2022.

 Pseudomonas aeruginosa isolates were obtained from 44 females and 51 males. Of all isolates, the WHONET analysis showed that resistance to imipenem and meropenem was 87.4% and 64.2%, respectively. The WHONET database can be an appropriate software for analyzing and monitoring bacterial susceptibility and resistance, especially for critical priority bugs such as P. aeruginosa.