The effect of oral glucose solution on pain intensity of newborn immunization

Unfortunately, a little attention was paid to importance of newborn pain problem but presently, according to identification of several complications, which is followed after painful procedures its importance has been revealed and considered more seriously by scientists. In addition, nursing and medical painful interventions in newborn wards is very common and advising non-drug treatments in order to decrease and control pain during painful interventions will be important. This study aim was to determine oral glucose effect on newborn pain intensity. This study as an applied research was done on 93 newborns that were divided in three groups equally consisting of two experimental groups and one control group randomly. This study was a double-blind clinical trial and to collect data, a sample selection form and newborn pain measurement scale (NIPS) were used. One experimental group (Group1) took 2ml glucose 25% solution orally and the experimental group (group 2) was given 2 ml sterile distillated water orally (placebo) during 30 seconds, and 2 minutes after glucose solution and distillated water taking, B- hepatitis vaccine was injected. After injection, behavioral newborns pain scale was surveyed. No interventional treatment was performed in control group (group 3). SPSS software chi-square and statistical tests (LSD, ANOVA) were used to analyse data. The findings showed that the score of pain in the newborns that took glucose 25% was significantly lower than the other groups. The average of pain scores for group1, group 2 and group 3 were calculated 2.90, 5.29 and 5.45 respectively. The Comparison of pain intensity in these groups showed that the difference between group1 with group2 and group3 was significant (P=0.0001) but there was no significant difference between group 2 and group 3 was not significant (P=0.664). Prescription of glucose 25% solution orally during injection could induce a considerable analgesic effect. By noting that the glucose solution is safe, cheap, and available, it can be used as an analgesic solution when performing painful procedure on newborn such as vaccination.