evaluation of the effect of gamma ray on erythroid cells in bone marrow oaf Balb/c mice on the base of micronucleous test
Author(s):
Abstract:
In this paper, effect of gamma ray on erythroid cells of bone marrow such as polychlomatic erythrocytes (PCE) and normochromatic erythrocytes (NCE) was assessed after exposure to doses 1, 2, 5, 7. 5,10 Gray. Twenty four hours after exposure, mice were sacrifrced by cervical dislocation and bone marrow of their femurs were extracted. Then, the changes in NCE, PCE and micronucleus cells caused by radiatlon were considered Standard staining and optical microscope have been used to count cells without and with Micronucleus.Result shoed that, relative decreasing of the number of PCE and increasing of the number of micronucleus up to dose of 2 Gray, which showes the cytotoxic and clastogenic effect, respectively. In doses higher than 2 Gray, these changes were not continued, Thus PCE increasing was seen in doses between 5 and 7.5 Gray and its decreasing was seen between 7.5 and 10 Gray. At the same doses, the number of micronucleus was also decreased. Overall, we concluded that Probably defensive mechanisms of Balb/c mice in doses higher than 2 Gray are stimulated Too. Therefore they have more resistance against the destructive gamma ray effects.
Language:
Persian
Published:
Journal of Military Medicine, Volume:5 Issue: 2, 2003
Page:
121
magiran.com/p445127
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!