Laryngeal Polyp as the First Manifestation of Hypothyroidism: A Case Report

Hypothyroidism rarely presents only by hoarseness. Hoarseness is induced by various etiological factors including CNS nucleus involvement, crycothyroid muscle edema, TVC edema, and at least commonly due to laryngeal polyp. In this report, we present a case of a 50 year-old women with laryngeal polyp with hypothyroidism. She was presented with a 1 year history of hoarseness without any improvement to various medical treatments and with no sign or symptom denoting hypothyroidism. Laryngeal examination revealed a giant polyp. Para-clinical assessment showed subclinical hypothyroidism and histopathology was compatible with hypothyroidism deposition (hyaluronic acid collection). Hypothyroidism and Hashimato thyroiditis was proven by clinical and paraclinical assessment in 6 months follow up. Hypothyroidism had predisposed laryngeal polyp formation. Laryngeal polyp is an irreversible stage of hypothyroidism induced hoarseness and caused by mucopolysacarides and hyaluronic acid collection. As regards the high incidence of hypothyroidism especially in premenopose women, it is important to consider thyroid abnormality in the face of hoarseness in such patients and perform thyroid function tests.