Effect of Preoperative Fasting on Hemodynamic Status of Elective Hysterectomy Patients with General Anesthesia

Introduction & Preoperative fasting for performing elective operations can lead to a metabolic state which is unfavorable for patients. The aim of this study was to determine the outcome of preoperative fasting on hemodynamic status of patients with elective operations by general anesthesia. This is a descriptive study performed in Tabriz University of Medical Sciences, in Alzahra educational and therapeutic center on 60 ASA class I, and II patients candidate for elective hysterectomy in 1385. Simple sampling method was used for recruitment of patients and a questionnaire was used for data collection. Collected data were analyzed by student t-test, using SPSS software. The average age of the patients was 47±5.69 years and their body weight was 56±7.56 kg. The average of fasting time (in hours) was 12.66 for operations performed in the morning and 16 for evening surgeries. Changes of hemodynamic parameters (including systolic and diastolic blood pressure and heart rate) during 5 to 10 minutes of induction were significant during induction of anesthesia in comparison to baseline levels (p<0.05). For signs of dehydration, 25 (41.66%) of patients had dry mucosa and 14 (23.33%) cases complained of being thirsty. Urinary output during the first 30 minutes of surgery reported to be less than 15 ml/hr in all cases. No significant changes in body temperature were observed in studied patients. Results of this study revealed that preoperative fasting before elective operations for prevention of aspiration must be considered in order to decrease its effect on hemodynamic status of patients especially during induction of general anesthesia.