Esthesioneuroblastoma: Analysis of cases

AbstractThe purpose of this study was to analyze the natural history, treatment and prognosis of Esthesioneuroblastoma (ENB), a rare malignancy of the head and neck, based on the literature review. A retrospective study conducted on ENB patients who were treated at Qhaem and Omid hospitals, since 994 to 004.Eleven patients (mean age 44 years) with ENB identified and analyzed. The patients generally presented with unilateral nasal obstruction (7.7%) and epistaxis (63.6%). The right side was affected in 36.4% of patients. While the left side was involved in 54.5% and both side of the nasal cavity were involved at presentation in 9.%. Kadish stage C was seen in 54.5% of patients. No patients had distant metastases and two patients (8.%) had neck lymphadenopathy at presentation. Surgery was performed in 8 patients (7.7%). Radiation therapy was employed in cases and chemo-therapy in 3. Recurrence occurred in one patient. Five-year survival was 80% and ten-year survival was 48%.ENB is rare tumour that is potentially curable by surgical resection and radiation therapy.