The effects of arsenic on blood cells in rat

Environmental pollutions is a global problem which is the most important goals of researchers. In developing countries, the pollution of the heavy metals in the environment is a serious problem. Arsenic is one of the heavy metals in the environment. In addition to natural resources and as a result of using these metals in various industrie-products like paints, ceramics, etc..., the environment is getting more polluted than any other time. By entering this element in to the body, it causes several side-effects in organs such as digestive, nervous, renal, reproductive and cardiovascular system. Lauwerys et.al (1995) showed that rats exposing for short periods to the pollution of heavy metals could have unfavourable effects such as damaging of the enzymes system. The aim of this study is to find the effects of arsenic on blood cells in rats. To perform these experiments, 16 rat were devided in to 4 groups. It is notable that each group were kept separate. The first group was exposed to 50mg/l arsenic in drinking water. The second and third groups were exposed to 100mg/l and 200mg/l of arsenic in drinking water respectively. The fourth group was considered as the control group. After 2 months of treatment, blood-sampling was done and some laboratory tests were conducted on the blood cells. The analysis showed that different concentration of arsenic have special impact on the blood cells. these impacts are non significant change in the red blood cells, but they are quite meaningful in some blood whit cells such as monocyts, lymphocyte, basophile and eosinophils. The reason of non significant in rats red blood cells is in realation to more resistance of rats to environmental pollution compare to the humans.