Predictive Value of Roll-Over Test and BMI in Early Diagnosis of Pre Eclampsia

Preeclampsia is a major cause of prenatal and maternal morbidity and mortality. The early diagnosis of pre-eclampsia remains one of the most important functions of antenatal care. By predicting pre-eclampsia maternal and infantile prenatal mortality rates are expected to be lowered. This was a prospective study with randomly sample that was performed on 400 primiparous women between the 28 and 32 weeks of gestation. At first weight, height, blood pressure on left position and supine position were measured then these women were followed until delivery. Of total 400 women, 23 women developed pre-eclampsia. Mean difference of diastolic blood pressure in left position and supine position and BMI were significantly different in the two groups (P< 0.05). Using the ROC, BMI higher than 28/88 showed a sensitivity of 61%, specificity of 92%, positive predictive value of 33% and negative predictive value of 97%. Roll-over test higher than 20 mmHg showed a sensitivity of 52%, specificity of 95%, PPV= 39% and NPV= 97%. When the two tests were positive they showed a sensitivity 30%, specificity 99%, PPV= 58% and NPV= 96%. The combination of Roll-over test and BMI with low sensitivity has high specificity for rulengout pre-eclampsia.