Evaluation of Antibiotic susceptibility & Resistancy in Urinary Infections Imam Khomeini Hospital complex-Tehran

Urinary tract infection (UTI) is one of the most common infectious diseases in the world. We performed a study to determine the spectrum of bacterial etiology and antibiotic resistance pattern of the uropathogens that cause community acquired UTI. Urine samples taken from 32400 qualified for the study Were collected through three years. The samples were submitted to the necessary tests And after separation of the infection agents the sensitivity to antibiotics test was Conducted in a standard method. Out of 32400 eligible samples 5400 (16. 6%) had positive culture. Ecoli (44. 5%) and klebsiella pneumoniae (8. 5%د) represented the bulk of separated organisms. Ecoli is the most sensitive to nitrofurantoin (76%) and the most resistant to penicillin (94%) and ampicillin (89%). In general the most sensitive was imipenem (99%) and the most resistant were penicillin (89%) and ampicillin (84%). Escherichia coli and klebsiella constitute the bulk of separated organisms in this study and the infective urinary agents are the most resistant to cotrimoxazole and fluoroquinolone and the most sensitive to nitrofurantoin and imipenem. In cases the urine culture is not available or it is not possible to wait for the culture response these antibiotics are the best choice to begin the treatment.