Effects of Intravenous Magnesium Sulfate Administration on Postoperative Acute Pain Followed by Spinal anesthesia

Magnesium is an inorganic ion. There are several products containing magnesium and it has a number of therapeutic properties. Magnesium-sulfate is a very common product and its usefulness has been proven in field of anesthesiology. This study looks at the effect of prescribing intravenous magnesium-sulfate on acute pain following orthopedic surgery of the lower extremities in patients anesthetized with spinal anesthesia method. In this double-blind, randomized, placebo-controlled clinical trial, 60 patients were selected and were randomly divided into 2 groups. Efforts were made to place both groups under the same method of anesthesia and other variable were kept constant to the best of our ability. One group received intravenous magnesium sulfate under a given protocol and the second one received the same volume of placebo, intravenously. To present the results Mean (±SD) was used and the P-value of less than 0.05 was considered statisticaaly significant. There was no difference between the 2 groups under basic variables. Pain reported by the first group who received magnesium sulfate was significantly less at the 1st, 3rd, 6th, and 12th hours after the operation in comparison to the group who received placebo. At the 18th and 24th post-operation hours, there was no significant difference between the 2 groups. Receiving intravenous magnesium sulfate following lower extremities orthopedic surgery would significantly reduce the pain in the first few hours after the operation.