Study of histopathological effects of isoprenaline on female cat parotid salivary gland

The salivary glands due to their various functions always have been important in researches. In this research, histological structures of cat parotid gland in normal condition and under the effect of isoprenaline have been studied. Ten adult female cats for this study were used in two groups of control and treatment. Chronic treatment of isoprenaline with dosage of 1/6 mg per cat for twenty days revealed remarkable changes on weight and cell structure of parotid gland. In treatment group the mean weight of parotid gland has been increased 1/8 fold of control group. In histopathological studies of parotid gland at light microscopic level, in control group the secretary units of parotid gland was compound acinar and purely serious. In treatment group, histopatological changes such as hyperplasia and hypertrophy of secretary units were observed. As a result, we concluded that the effect of isoprenaline on cat parotid salivary gland is similar to other animals such as rat, mouse and rabbit.