Determining the Antibiotic Resistance Pattern of Urinary Isolates of Escherichia coli and Prevalence of Extended Spectrum ß-lactamases (ESBLs) among them

Background and Increased spread of antibiotic resistance and treatment failure among Escherichia coli isolates, most common agent of urinary tract infection, can be related to the increasing prevalence of expanded spectrum β-lactamases (ESBL) clinical isolates. The present study was conducted to examine the antimicrobial resistance of urinary isolates of E. coli in Mashad and to detect the ESBL producing strains among them. Methods and Materials: In this descriptive study, 109 isolated E. coli were identified using differential biochemical experiments, from urine samples of hospitalized patients in Mashad hospitals (Ghaem and 17-Shahrivar Hospitals). The antibiotic susceptibility was examined by disc diffusion method according to Kirby-Bauer standards. Detection of ESBL producers were done by double disc method. Data were analyzed by Statistica software using Chi-square. Findings with p