Effect of cinnamon extract on the number of spermatocyte and spermatozoa cells in mice

Cinnamon is a plant with scientific name Cinnamomum zeylanicum Nees which belongs to Lauraceae family. This plant has many pharmaceutical effects and one of the most important ones is increasing sexuality. This research considered the effects of Cinnamon bark extract on structure of testis tissue and number of sexual cells in Balb/c mice. First, samples separated randomly to six groups (four treatment groups and two groups as control and placebo), each group contained eight samples in a same condition. Cinnamon hydro-ethanol extract provided in different dose (50,100, 200 and 400mg/kg/2day) and injected intraperitonealy for 20 days to treatment groups and also used normal saline and ethanol for injecting to placebo group (Zero dose). The most important parameters evaluated in this research included: the testicles weight changes, probably histological changes in testis and change in number of sexual cells compared to control group. The number of primary spermatocytes and assess of histological properties were done with provided sections of seminiferous tubules using light microscope. Also, the spermatozoids were counted using hemocytometer lamel. The analysis of results indicated that no significant differences were observed in weight of testicles and histological properties in any group. The number of primary spermatocytes and spermatozoids could be increased significantly in dose of 100, 200 and 400mg/kg/2day compared to other groups. Results indicated positive effect of cinnamon extract on male reproductive system because number of sexual cells increased significantly.