Evaluation the Treatment Effect of Vitamin B1 in Primary Dysmenorrhea

Primary dysmenorrhea with prevalence of 90% is the one of the most gynecologic problems and it is one of the important ethiology of decrease of quality of live in women. The treatment is varity cocp, NSAIDS (common treatment) The use of acupuncture. Tens, Laparascopic surgery, vitamin B1 acid -3 omega, transdermal N.G. (nitroglycerin) in the studies were evaluated but the number of cases and the period of follow up is limited. In the study in India with Gokhale and et.al in 1996, the curative Rate of treatment with Vitamin B1 was proved. In this study we evaluated the treatment effect of Vitamin B1, and follow up the patients 3 months later and 6 months after the onset of treatment.

In this study 2 years between 1999-2001 a Randomized double blind placebo controlled study, one group (118-n) received Vitamin B1 (100 mg) and other group (124=n) received placebo daily in the onset of three month treatment and end of treatment and 6 months later of onset of treatment the patient is calculated with visual analgesic scale and cox-menstrual scale.

The prevalence of primary dysmenorrhea in the population of this study was 51/9% mean age of menarche 13/3 year. The rate of NSAID using is 63/1%. 85/5% of patients had irregular menses. The prevalence of premenstrual sign. And the signs correlated with dysmenorrhea were evaluated between two groups of treatment evaluated 3 months after treatment period in the placebo control care rate was 21% and in Vitamin B1 was 86/4% (chi=103.59 p value=0.000).

The results in this study were similar with the results of Gokhale in India. This treatment did not have any side effect and this treatment tolerated easily.