Keratic Precipitate Morphology in Various Uveitic Entities: A Confocal Scan Study

To characterize keratic precipitate (KP) morphology in different forms of uveitis. One hundred and twenty nine eyes of 93 patients with different forms of uveitis underwent confocal scan and the morphology of KPs were determined. Differences in KP morphologies among different uveitic groups were evaluated. Age ranged from 14 to 67 years (mean: 32.5±11.2) and 58 cases (62.36%) were female, 38.7% had bilateral uveitis. Almost all types of uveitis disclosed predominantly stippled and globular KPs. Dendritiform KPs were more common in infectious uveitis (P=0.053) and smooth-rounded KPs were significantly more common in non-infectious uveitis (P<0.001). Dendritiform KPs were observed more commonly in nongranulomatous uveitis than granulomatous ones (P=0.005). Smooth-rounded KPs were more common in chronic uveitis than acute forms (P<0.001). The predominant morphology of KPs in Fuchs heterochromic iridocyclitis (FHIC) were dendritiform (80.0%) and infiltrating (78.0%). The most commonly observed morphology of KPs in intermediate uveitis were dendritiform (56.3%) and smooth-rounded (56.3%). Cruciform KPs were more frequently seen in cases with FHIC (60.0%). Morphologic features in bilateral cases were similar. KP morphologies are diverse in different forms of uveitis. Some forms of KPs are less specific such as globular and stippled which exist in almost all types of uveitis. Confocal scan can play a potential role in differentiating infectious from noninfectious uveitis and granulomatous from nongranulomatous uveitis.