Evaluation of Relationship between Bacterial Vaginosis and Embryo Implantation and Early Abortion in Infertile Couple Curing with Intra Cytoplasmic Sperm Injection

Today there is a significant progress in the treatment of female infertility but there is no main improvement for the rate of implantation and live birth. This is because of non-implantation and early abortion that lead to decrease the rate of live birth. Genital infections such as bacterial vaginosis are common cause of this problem.Distinction and treatment of bacterial vaginosis is easy and non-expensive. Treatment of bacterial vaginosis could results in improving the rate of implantation and then live birth. We considered 209 infertile women treated with ICSI (intra cytoplasmic sperm injection). This study was performed in infertility clinic of KOSAR hospital affiliated to Urmia University of Medical Sciences, Iran.Before transferring of embryo, a sample was taken from posterior culdesac secretions by sterile cotton swap and fixed it on lamella. Then bacterial vaginitis was graded by a pathologist. The relationship of bacterial vaginosis with implantation and early abortion was studied. Data were entered into SPSS software and analyzed by t-test and Chi-Square test. p <0.05 is considered statistically significant. Bacterial vaginosis was significantly more frequent in patients with tubal and ovulatory disorder (p =0.013). In women undergoing ICSI, bacterial vaginosis was not associated with decreased conception rate (p =0.892) and with increased rate of early pregnancy loss (p =0.44).Conclution: Bacterial vaginosis is prevalent in women with infertility. It is also the most important cause of infertility in patients with tubal and ovulatory disorder. Bacterial vaginosis does not affect fertilization rate.