A Comparison of Prophylactic Effect of Ondansetron and Meperidine in Reducing Shivering Prevalence Following Elective c/s by Spinal Anesthesia Method

Postoperative shivering is one of the common problems after anesthesia and can cause many complications such as heart disease, increased intraocular pressure, increased intracranial pressure and other problems. Various methods and drugs have been used for the prevention of postoperative shivering. In this study, we have investigated the pretreatment effect of ondansetron and meperidine in reducing shivering after cesarean elective by spinal anesthesia. In this double-blind study, 100 volunteered patients for cesarean elective using spinal were blocked and classified randomly into two groups. After the baby was born, 8 mg/kg ondansetron for the first group (O) and 0.4 mg/kg meperidine for the second group (M) was injected slowly. MAP, Heart rate and SPO2 were measured and recorded before the operation, during the operation and after the operation. The shivering or its absence was recorded for 20 minutes after the operation by a recovery nurse. The incidence of postoperative shivering was 10% in ondnasetron group and 24% in meperidine group. But there was no significant difference between the two groups. There was not a significant difference between the effects of ondansetron and meperidne groups.