Effectiveness of Lazarus multimodal therapy on expanded disability status in patients with multiple sclerosis

The purpose of this study was to investigate the effectiveness of Lazarus multimodal therapy on expanded disability status of patients with multiple sclerosis. This study was a quasi experimental research administered in 2009. All convenience participants were selected from MS outpatient clinic of Qazvin city. For this aim, some of the patients in Qazvin were selected by convenience sampling. After primary assessments, 40 patients were selected and randomly allocated in two groups (20 in experiment group and 20 in control group). From 20 patients of experiment group, 16 patients completed the treatment. During 3 month Lazarus multimodal therapy was administered in the experiment group in twelve sessions each of them length 90 minutes. Expanded disability status of patients was evaluated by a neurologist before and after treatment. Data were analyzed by Mann-Whitney U test. The results indicated that Lazarus multimodal therapy had significant effect on EDSS score (P=0.035), bowel-bladder (P<0.0005), and cerebral functional systems (P=0.014). This treatment had not significant effect on pyramidal and visual systems. Lazarus multimodal therapy is effective in decreasing disability of patients with multiple sclerosis.