Outcomes of Stereotactic Brachytherapy (temporary 125Iodine seeds) for the treatment of low grade glioma tumors in Shohada-Tajrish Hospital between 2004 and 2011

Treatment of low-grade glioma (LLG) is one of the problems of neurosurgeon. According to reports, treatment of LGG tumors has been successful with stereotactic brachytherapy (SBT with temporary 125Iodine seeds). Due to the lack of reported experience in our country in this regard, this study was conducted on patients treated in Shohada-Tajrish Hospital between 2004 and 2011.

This case series was conducted on consecutive patients with diagnosed LGG tumors treated with SBT (125Iodine seeds). Patients follow-up were at least 6 months. Survival of patients was assessed with the Kaplan-Meier method.

During the study period 8 patients (7 male and 1 female) with a mean age of 31.1±10.6 y were treated. One patient died due to respiratory and cardiac problems. The overall survival was 42% and 7 patients were alive by the last follow-up. ‍

It seems using SBT (temporary 125Iodine seeds) in the treatment of LGG tumors is acceptable. It is recommended to compare the efficacy of this method in newly diagnosed patients compared with those who did not respond to the previous treatments.