Assessment of correlation between CAD and CRF in patients candidate of kidney transplantation in Taleghani hospital

Patients with chronic renal disease have an increased risk of developing coronary artery disease (CAD). The cardiovascular mortality of dialysis patients is 10-15 times higher compared with general population. Renal transplantation has been shown to improve the quality of life and survival in recipient. However, with increasing number of people joining the waiting list, there is an increasing effort to carefully screen patients for their suitability to be a potential recipient. Consequently, Cardiac evaluation prior to renal transplantation has been a pillar of this screening process. In this study, 75 pretransplant dialysis patients with high risk criteria for cardiovascular events (including history of diabetes mellitus, age>50 y, clinical symptoms and signs of CAD or ST-T change in ECG) were evaluated through coronary angiography with sildenger method. There were 75 patients (44 men and 31 women) with mean age of 52 y. Obstructive CAD was demonstrated by coronary angiography in 50 patients (66.6%) and 25 patients (33.3%) showed normal coronary arteries or Mild CAD. Among 33 diabetic patients, 29 (90.5%) showed obstructive CAD and 4 (9.5%) were normal or showed Mild CAD. From 42 nondiabetic patients, 21 (50%) showed CAD and (50%) were normal or showed Mild CAD. ‍ According to this study, for diabetic renal transplant candidate, a baseline coronary angiography for risk stratification of CAD is useful and cost-effective, but nondiabetic patients remain a subject of debate and need more evaluation.