Investigation effect of the tribulus terrestris extract on spermatogenesis in the rat

The previously believed was Tribulus terrestris increase sexual function and libido in men, more than have other pharmacological properties. benefitical of herbal drug have to evidenced with clinical and bodily measure.The aim of the current study was to investigate the effect of Tribulus terrestris extract on primary spermatocyte on rat. Material and method of study: In this experimental study used Thirty-five mature male wistar rats with average weight 180 ± 10 g and age 2-3 month, were randomly divided into five groups of seven each. Group I served as a control and group II as a vehicle group (normal saline, 2.5 ml) and groups III, IV and V were treated with three different doses of TT extract (2.5, 5 and 10 mg/kg body weight, respectively), orally, once daily for 8 weeks. After the last treatment, rats were sacrificed and their testis were removed, fixed and studied with light microscope. The data analyzed based on ANOVA test.

The results showed that the mean number of primary spermatocytes in 3th experimental group (10 mg/kg/body) compared with the control group increased significantly (p <0.01). But Tribulus terrestris extract no effect on the mean number of primary spermatocytes in other experimental groups. Discussion and

above result showed that tribulus terrestris could balance action of male reproductive system and maybe used up for treatment of male infertility, with effect on the testis spermatocyte.