Correlation between Procalcitonin, CBC, ESR, and CRP before and after Treatment of Systemic Inflammatory Response Syndrome in Children Aged 1-36 Months

Systemic inflammatory response syndrome (SIRS) is one of the important causes of morbidity and mortality in pediatrics. Infection is the main cause of SIRS. The aim of the present study was to evaluate the correlation between procalcitonin (PCT), CBC, ESR and C-reactive protein. Fifty children, aged 1-36 months, hospitalized in pediatric ward in Besat hospital, Sanansaj were studied. In all patients, PCT, CBC, ESR and CRP were measured. We used Pearson correlation coefficient to evaluate the correlation between CBC, ESR, CRP and PCT before and after treatment of SIRS. In the first day (before treatment), the correlation between PCT and CRP was strong and between PCT and ESR was weak. But there was no correlation between PCT and WBC. In the third day of treatment, there was no correlation between PCT, WBC count, ESR, and CRP. To confirm the diagnosis of SIRS prior to the treatment, procalcitonin and CRP are of high importance. However, procalcitonin is a better marker in fallow up.