The Effect of Short Term Vitamin E Supplementation on Plasma Nitric Oxide, LDH, CPK Changes in Untrained Male Followed by Resistance Training

The purpose of this study was to investigate the effect of short term vitamin E supplementation on nitric oxide responses and some muscle damage indices in untrained male followed by resistance training. Twelve untrained students that resident in university dormitory volunteered into this study and were randomized in vitamin E (n=6) and placebo (n=6) groups. Designed training Protocol was circular and with %75 1RM was done. Venous blood samples were drowning on the condition of minimally 12h fasting in three periods, pre-exercise, immediately after the exercise and 24h post-exercise. Each subject of experimental group received 14 vitamin E capsules (800 IU/day). Again after one -week supplementation, in minimally12h fasting, blood sampling was repeated. Results. resistance training increases NO level in both groups. Vitamin E supplementation decreases significantly NO level immediately after training (P<0.001); moreover, NO level changes between experimental and placebo groups were significant after 24h training (P<0.008). These findings also indicated that CPK level in experimental group following supplementation in base level and immediately post-exercise was decreased. Short -termvitamin E supplementation did not have any significant effect on LDH levels after supplementation. Conclusion. vitamin E supplementation may have beneficial effects on decreasing oxidative stress and free radical and cause decreasing muscle damages followed by acute resistance training.