The Effect of Aerobic Training and Vitamin E and C Supplementations on GSH Levels, SOD and GPX Activities in Pregnant Rats

The purpose of study was to determine the effect of aerobic training with and without vitamin supplementations on SOD and GPX activities and GSH in pregnancy period. Fourteen female rats (with age 3 month and weight 145-160 gr) divided to 4 groups after pregnancy: training (T), training and supplement (T+ S), supplement (S), and control (C) groups. The animals kept in standard laboratory conditions and their availability was free to food and water. S and T+S groups used supplemented food (600 mgr vitamin E and 1 gr vitamin C per Kg) and T and T+S groups participated in aerobic training on treadmill on overload principle. ANOVA used to analyzing data. Results showed there are not significant differences between GSH levels (P=0.054) and GPX activity (P=0.293) but SOD activity was different significantly (P=0.002). Pre and Post test comparision showed GSH were not different in groups but SOD activity were different in T (P=0.000), T+S (P=0.012) and S (P=0.001) groups. Also, GPX activity decreased in C group (P=0.036) but it increased in experimental three groups. Generally, study showed aerobic training, vitamin supplementation and training with supplementationcan increase antioxidative system capacity.