Relationship between serum C-reactive protein and obesity in children

Obesity predisposes individuals to cardiovascular diseases.The aim of this research is to study CRP as a prognostic inflamatory factor in children with obesity and overweight in comparison with non obese ones. We investigated 80 children aged 8- 10 years assessing obesity as case group and 80 non-obese children as control group. Serum level of Cholesterol, triglycerides, low-density lipoproteins (LDL), high-density lipoproteins (HDL) and C-reactive protein were measured. Finally the data were analysed using SPSS software, X2,t and fisher tests. The results showed that there were significant correlations between CRP in obese children than non-obese children. 31% of the case group had positive CRP (PV=0.000001). Lipid analysis showed significant correlations between mean Cholesterol level and CRP in obese and non-obese children. Mean Cholesterol level in posetive CRP group was 201.9 mg/dl but mean Cholesterol level in control group was 183.1 mg/dl. (P=0.04,T=-2.1) This study showed significant correlations between CRP and obesity in 8-10 years old children.