مجله دانشکده پزشکی اصفهان
پیاپی 573 (هفته اول تیر 1399)

The main treatment for thyroid cancer surgery is total thyroidectomy based on neck incision, and then, detachment of platysma flap; but this incision causes a long scar that can affect patients' satisfaction and impair their quality of life. In this study, we aimed to compare the scar of collar incision in thyroidectomy surgery using under- or over-platysma flap with or without muscle repair.

 In this clinical trial study, 160 patients selected in Alzahra and Imam Reza hospitals, Isfahan, Iran, during 2017-2018, were divided into four groups using randomized blocks method. In groups A and B, platysma flap was used; in groups C and D, subcutaneous flap was used on the platysma; in groups A and C, platysma muscle was repaired; and in groups B and D, platysma muscle was not repaired. Then, these four groups were followed up according to Vancouver standard score, and patient satisfaction with the beauty of the scar was assessed after 6 months.

Vancouver score with subcutaneous flap did not show a significant difference, as a result of platysma flap; but platysma repair showed significant difference. We found that at the end of the study, the levels of patient satisfaction (through five Likert rankings) were significantly correlated with their Vancouver scores.

 Both flaps are effective, but it is better to repair platysma muscle for patient satisfaction.

Exercise can be a supplementary therapy to treat seizures. However, there is little information on the extent of these effects in seizure-susceptible individuals. In this study, we investigated the simultaneous effects of aerobic exercise in the kindle and non-kindle rats with pentylenetetrazole (PTZ).

In this experimental study, 40 rats were divided in 4 groups of kindled with PTZ injections that performed aerobic exercise for 6 weeks, sedentary kindled with PTZ injections, non-kindled that performed aerobic exercise for 6 weeks, and sedentary non-kindled. The non-kindled groups only received PTZ before and after 6-week period. 24 hours after the 6-week period, all groups received PTZ, and seizure parameters including stage 4 latency (S4L), stage 5 duration (S5D), and seizure duration (SD) were compared with before 6-week period. Repeated analysis of variance (ANOVA) and Bonferroni post hoc test were used for data analysis.

In non-kindled animals, aerobic exercise reduced seizure parameters of S4L (P < 0.001) and SD (P < 0.050), and removed the generalized seizures. In kindled rats, it increased the latency time until the seizure onset (P< 0.001), and decreased the S5D and SD parameters (P < 0.001).

The results showed that 6 weeks of aerobic activity reduced epileptic behaviors in kindled and non-kindled rats.

According to the World Health Organization’s (WHO) recommendations, washing hands frequently with soap and water for 20 seconds is an effective way to prevent COVID-19 infection. Every Muslim is obliged to perform ablution before prayers. Wash your hands up to your wrists once, rinse your mouth and nose three times each, wash face from head to chin twice and hands from elbow to fingertips once, and anoint part of the head and legs. However, in each complete ablution, washing is performed 10 times, and in each day, 30 times. This wash cannot replace the WHO guidelines, but it can be effective in preventing COVID-19 infection.