Razavi International Journal of Medicine
Volume:9 Issue: 2, Spring 2021

We undertook a systematic review of the literature to determine the efficacy and safety of Imatinib in the restriction of activity and effective treatment of patients with aggressive fibromatosis (AF) and pigmented villonodular synovitis (PVNS) and their recurrence. We searched studies in the PubMed and Cochrane collaborative library at all levels from 2010 to April 2019. Two independent reviewers evaluated the articles according to the predefined criteria and extracted the related data. Primary outcomes associated with tumor size shrinkage, relapse and overall survival along with secondary outcomes such as pain, quality of life, and side effects were investigated. 112 studies were evaluated out of which only 6 studies that covered original studies and case reports were entered into this systematic review. A total of 79subjects had participated in these six studies with an age range of 22 to 41 years old. In five studies, participants had a primary tumor and in one research they reported relapse. The recommended dose was 400 mg/day, which was usually continued for 4 to 12 months. The tumor size shrinkage and low side effects of drugs have been reported. According to the results, no systemic treatment for PVNS and AF has been approved so far, but many studies have demonstrated the efficacy of Imatinib in the treatment of these diseases. However, further studies are required for optimal treatment and combined therapies.

Most deaths occur unpredictably and usually outside of health care facilities; while could be predicted by Cardiopulmonary Resuscitation (CPR). Whatever, the success rate of this procedure is affected by many factors and the aim of this study was to evaluate CPR outcomes and determine theassociated factors. This descriptive retrospective study was conducted in 2018 in a private hospital in Mashhad. Census method was used for sampling, and all the patients who underwent CPR were included in the study. Meanwhile, those who had signs of death and/ or those with incomplete medical records excluded from the study. Moreover, data were provided through the Statistics, Medical Records as well as Quality Improvement units. In this study, 394 medical records were evaluated, out of which 224(56.9%) were male and 170(43.1%) were female. Totally, 96(24.4%) successful and 298(75.6%) unsuccessful CPR were recorded. There was a significant correlation between age of the patientand successful CPR (P=0.011). Results of the study showed that the success rate of CPR will be higher, if the patient is young, duration of CPR is short, and the patient has a non-cardiac underlying disease.

Cancer is a disorder in the rate of cell proliferation and differentiation that can occur in any tissue of the body and at any age, and attacking healthy tissues of the body causes severe disease and consequently death. The aim of this study was to analyze the structural equations of biological indicators of stress based on perceived stress mediated by emotional regulation in patients with gastrointestinal cancer. In terms of research method, this research is descriptive-correlational research of structural equation type. The statistical population of the present study included all patients with gastrointestinal cancer who were referred to Reza Medical Center-Mashhad and Ibn Sina Hospital-Tehran and were diagnosed with this disease based on the patient's file. The sample of this study included 250 people from the mentioned community, which was done using a non-random and available sampling method. Data in this study were obtained using the Perceived Stress Scale, Cognitive Emotion Regulation Questionnaire, and Biological Indicators of Stress. Data were analyzed by structural equation modeling and Pearson correlation using SPSS.22 and AMOS.22 software. The results showed that perceived stress (β=-0.37, p <0.001) directly emotional regulation. Also, emotional regulation (β=0.54, p <0.001) had a direct effect on biological stress indices. Emotional regulation played a mediating role in the relationship between perceived stress and biological stress indices (RMSEA:0.001; AGFI:0.93). It can be concluded that the structural model of biological indicators of stress in patients with gastrointestinal cancer based on perceived stress mediated by emotional regulation has a good fit.

Considering that the health and illness of women can directly affect the general health of the family and society, and the problems originated from this disease not only affect the patients, but also exert a deleterious effect on the members of the family and undermine the foundation of the family. Thus, research on factors associated with the psychological issues of these patients can urge policy makers and healthcare professionals to pay greater attention to this issue. The aim of this study is to determine whether the quality of life of patients with breast cancer could be predicted by spirituality, self-forgiveness and self-blame.

This is a descriptive correlational study in which 120 cancer patients admitted to two university hospitals were selected using cluster-sampling method. The research instruments were the Paloutzian and Ellison’s Spiritual Well-Being Scale (1), self-forgiveness and self-blame scales and World Health Organization Quality of Life questionnaire. According to the level of data and statistical assumptions, multiple linear regression was used to test the hypotheses

The results of statistical analysis showed that the components of spiritual wellness, existential wellness, anxiety control and realistic perception were related to the quality of life at a significantly level of 5%. The positive value of these coefficients actually indicates that by improving these components, the quality of life could be enhanced. Also, it was found that negative attitude and self-blame were in a negative relationship with the quality of life.

The present study investigated the relationship between spirituality, self-forgiveness and self-blame with quality of life, with the results indicating that personal-level variables, i.e. spirituality, self-forgiveness and self-blame affect the quality of life

Given the importance of health tourism in Iran and the body of problems surrounding the implementation of health tourism along with the challenges of attracting tourism in Iran, after an analysis of the external environment based on PESTEL and PORTER methods and internal environment based on performance indicators and EFQM method, along with an analysis of high-level documents and stakeholders, we determined to formulate a strategy of health tourism supply chain in Razavi hospital of Mashhad in through an experimental study. Strategies were developed using SWOT matrix are based on comments and views of health tourism experts. They were then prioritized by QSPM matrix and following the implementation of strategies, strategic objectives and indicators were determined as a balanced scorecard. The results suggest that the use of above techniques can contribute to health tourism industry. 

Type 2 diabetes is a chronic and complex disease. This study aims to compare the effectiveness of stress management and acceptance and commitment therapy on psychological capital in patients with type 2 diabetes. The present study was a quasi-experimental study with pre-test, post-test, and follow-up design with a control group. The statistical population of the study consisted of all patients with type 2 diabetes referred to Milad Hospital in Tehran in 2019. In order to form three groups using the purposive sampling method, 90 patients were selected first by convenience sampling method, and then 30 patients were randomly grouped in the first experimental group and 30 in the second experimental group, and 30 in the control group. Follow-up phase was performed on all three groups three months after the post-test. The research instrument was The Lotans Psychological Capital Questionnaire (2007). Data were analyzed using a mixed analysis of variance by Spss.22. The results showed that stress management and acceptance and commitment therapy had a significant effect on psychological capital components in patients with type 2 diabetes compared to the control group (p <0.00). Also, the mean scores of post-test and follow-up of hope component in the acceptance and commitment group increased more than the stress management group (p <0.00). It can be concluded that stress management and acceptance and commitment therapy were effective in psychological capital in patients with type 2 diabetes. Acceptance and commitment therapy was more effective than stress management on the hope component.

The diabetic patients experience a plethora of emotional problems besides physiological physical problems, which can affect the course of their disease. Therefore, the purpose of the present study was to investigate the effectiveness of compassion focused therapy (CFT) on alexithymia, adaptive behavior, treatment adherence, and Blood sugarof patients with type 2 diabetes. In this research, a quasi-experimental design with pretest-posttest and control group was adopted. The study population includes patients with type 2 diabetes in Ahvaz in 2020 that referred to my center. The sample size (n=30) was selected using availability sampling method, who were randomly and equally assigned to experimental (CFT), and control group. To collect research data, the Toronto Alexithymia Scale, the Psychosocial Adjustment with Illness Scale, the Treatment Adherence Questionnaire, and the Blood sugar test were used. The CFT group received 8 sessions of intervention (each for 2 h). Multivariate analysis of covariance was used to data analysis. The results showed that CFT had a significant effect on alexithymia (F=9/27, p=0/006), adaptive behavior (F=6/75, p=0/016), and treatment adherence (F=15/26, p=0/001) of patients with type 2 diabetes in the post-test. There was no significant difference between the experimental and control groups in Blood sugartest (F=0/08, p=0/786). Based on the findings, it can be concluded that CFT is effective in increasing the level of adaptive behavior and adherence to treatment.

Nowadays, attracting tourists and keeping them in a competitive environment, especially in the health tourist industry, has a high priority. Given the different behaviors of health tourists, analyzing their behavior is important. This research is applied in terms of purpose and descriptive method. Data mining methods and powerful Python tools have been used to analyze the data. The combined method of clustering algorithm and communication rules have been used to identify the pattern of tourist behavior. After analyzing the data, the motivation of foreign tourists to travel to Iran was determined and the selected destination was prioritized based on importance and according to the behaviors and different needs of health tourists, different travel packages were designed. By analyzing the behavior of tourists and clustering them according to the type of behavior in each cluster, it is possible to achieve strategies tailored to their needs and predict the future behavior of tourists through their past behavior and was informed of the threats, opportunities, strengths, weaknesses of the system.

The most common conditions leading to a stoma (abdominal surgery) include colorectal bowel cancers and inflammatory diseases. This study aimed to determine the effectiveness of acceptance and commitment therapy (ACT) on psychological distress and rumination in colostomy patients.

This study was a quasi-experimental study with pre-test, post-test, and follow-up with the control group. The statistical population of this study included colostomy patients referred to the psychosomatic ward of Imam Khomeini hospital in Sari in 2019, of which 50 were selected by convenience sampling method based on inclusion and exclusion criteria and were divided into experimental and control groups (each group consisted of 25 people). The experimental group was placed weekly in 8 sessions of 120 minutes. Data were collected using a demographic questionnaire, psychological distress scale (Kessler et al., 2002), and rumination response questionnaire (Nolen-Hoeksema and Marrow, 1993) and analyzed by covariance analysis SPSS.22 software. The significance level of the tests was 0.05.

The results of this study showed that acceptance and commitment therapy (ACT) was effective on psychological distress (p <0.001) and rumination (p <0.001) in colostomy patients.

Considering the positive effect of acceptance and commitment therapy (ACT) on psychological distress and rumination of colostomy patients, it is recommended to use these capacities and training in planning mental health programs, especially in colostomy patients.

Teddy bear hospital is a public health project for children with an easy to apply experiential method. We performed this project in Mashhad, Iran as a pilot study to compare the feeling of preschool children when facing doctors and hospitals before and after the project. Medical students took part in conducting this project in Razavi hospital that included different sections. Pre/post design test, using picture questionnaires’ was performed. Data analysis showed significant improvement in children feeling when facing hospital but not significant about doctors. Notably more children could recognize commonly used medical instruments: stethoscope and otoscope after the project.

The main feature of Major Depression Disorder (MDD) is mood swings between sadness (from minor disappointment to extreme despair) for several days, weeks, months, or even years. This work tries to compare the effectiveness of compassion-focused therapy and quality of life-therapy on self-criticism and psychopathological symptoms in patients with MDD. This work is a quasi-experimental study (pre-test, post-test, and follow-up test with a control group). The subjects include 45 MDD patients admitted in psychological advisory centers in Neyshabur, all of whom are selected by convenience sampling method and randomly divided into three groups: the compassion-focused therapy group, the quality of the life-therapy group, and the control group. The members of the CFT group and quality of life-therapy respectively received 8 and 10 therapy sessions, while the control group members were put on a waiting list. The research tools are as follows Self-Criticism Scale, Depression-Anxiety-Stress Scale (DASS-21), and Beck-Depression Inventory-II (BDI-II). The participants were tested before therapy intrusions, immediately after the sessions, and two-month after the ending session. Data were analyzed according to the variance analysis test by repetitive measurements and SPSS-24 Software. The results show that both therapies are effective in reducing self-criticism (p < 0.001) and psychopathological symptoms (p < 0.001); however, this effect was significantly higher in the CFT group as compared to the quality of life-therapy group (p < 0.001). Given the biological and psychological infrastructure of MDD, using quality of life-therapy and self-compassion approaches (in addition to medication) can be effective in reducing MDD symptoms.

Diabetes is one of the most common chronic diseases that has attracted the increasing attention of health professionals. The aim of this study was to evaluate the effectiveness of mindfulness-based therapy on resilience, psychological well-being, and blood sugar levels in patients with type 2 diabetes in Tehran. The method of this study was semi-experimental with pre-test, post-test and control group. The statistical population of the study consisted of all patients with type 2 diabetes referred to health centers in Tehran, from which 30 people were selected by convenience sampling method and randomly selected in the experimental group (15 people in each group). And the control group (15 people) were assigned. The mindfulness treatment experimental group was trained for 10 sessions of 90 minutes, and the control group remained on the waiting list. The instruments used in the present study included resilience (Connor and Davidson, 2003), psychological well-being (Ryff, 1980), and their blood glucose was measured by glycosylated hemoglobin test, which was used in two stages of pre-test and post-test. Data were analyzed using multivariate analysis of covariance and SPSS.19 software. The results showed that the intervention used in this study could significantly improve resilience (p <0.001). psychological well-being (p <0.001), and blood sugar (p <0.001) in patients with type 2 diabetes. It can be concluded that mindfulness-based therapy was effective in improving resilience, psychological well-being, and decreasing blood sugar levels in patients with type 2 diabetes.

Breast cancer as a source of stress not only affects the patient separately but also is a major challenge for family relationships in this situation. The aim of this study was to investigate the causal relationship between perceived stress, perceived social support, and resilience with emotional adjustment by mediating body image in breast cancer patients. In this descriptive correlational study, the statistical population of this study was cancer patients referred to Khatam hospital in Tehran from October to December 2019. Using the purposeful sampling method, 200 samples were selected by the Cochran formula. The instruments used in this study were the Perceived Stress Scale (1983), Perceived Social Support (1988), Resilience (2002), Emotional Adjustment (1961). The proposed model was evaluated using the path analysis method. Correlation tests such as Pearson correlation coefficient and regression test were used to test the relationships. Based on the results of this study, the proposed model had the goodness of fit. The results showed that all direct pathways were significant except for perceived social support. Nonlinear correlations between perceived social support and body image adjustment were reported to be 0.22, which was statistically significant at p Body image played a mediating role in the relationship between perceived social support, perceived stress, and resilience with life satisfaction

Diabetes has long-term complications and therefore affects the health of the community in addition to the individual. Diabetes can have significant psychological effects on health and delay the recovery of the disease. This study aimed to determine the causal model of health-related quality of life based on subjective well-being and sleep quality mediating by self-care behaviors in diabetic patients. This correlational study was conducted using the path analysis statistical method. The statistical population included all middle-aged patients with diabetes who were referred to the endocrinologists of Bushehr province in 2019, among whom 195 people were selected by the available sampling method. Data obtained by SF-36 Health-Related Quality of Life Questionnaire, Diabetes self-care questionnaire, Pittsburgh Sleep Quality Questionnaire, and Mental Well-Being Scale. The data were analyzed using the path analysis method using SPSS.22 and Amos.22 software. The results showed that both the variables of sleep quality and mental well-being through self-care had a direct and significant relationship with quality of life (p <0.001). The direct relationship between sleep quality and quality of life was not significant. But there was a significant direct relationship between mental well-being and quality of life (p <0.001). It can be concluded that sleep quality and mental well-being affect the self-care that the patient chooses, they can predict the quality of life of diabetic patients.