مجله دانشکده پزشکی زابل
سال چهارم شماره 1 (پیاپی 10، بهار 1400)

Chronic renal failure is a disabling condition with multiple complicationsuch as depression and anxiety; they are common in hemodialysis patients and have negatively effect on quality of life. In this study we investigate the prevalence of depression and anxiety in Zahedan hemodialysis patients.

A total 200 patients undergoing regular hemodialysis for more than six months included in this descriptive cross-sectional study. After consent The Hamilton Rating Scale for Depression and anxiety (HAM-D7) in a version translated into and adapted to Persian, were used.

The patients median age was (43.06 ± 16.11) years and 38.5% was male. Mild depression was observed in (15) 7.5%, moderate in (81) 40.5% and sever depression in (104) 52% of patients. In this study 19.5% (39) of patients has moderate anxiety and 80.5% (161) patients with sever anxiety.A significant correlation was found between duration of dialysis, older age and depression. But there wasn’t any relationship between age and duration of dialysis with anxiety. Anxiety and depression found without any significant differences in both males and females.

We found high level of depression an anxiety in Zahedan hemodialysis patients

Welding process is classified as one of the most widespread and widely used activities in industrial environments. Welding is one of the risky professions and the workers working in this sector are exposed to many risks. Identifying and evaluating the existing risks and managing them plays an important role in maintaining the health of workers and making their work environment healthier. The purpose of this study was to identify and evaluate the hazards caused by the use of devices in the welding process using the FMEA method in welding workshops in Zabol in 2021.

This cross-sectional analytical study was performed on 77 welding workshops in Zabol. In this study, in the first step, the main risks in welding workshops were identified and based on FMEA logic, for each risk caused by the machines, three indicators of severity, probability and vulnerability were identified. Specified. Then the prioritization criterion was determined and based on the number obtained from the RPN index, the risks were prioritized.

The findings of this study showed that in terms of risk priority in welding workshops, the highest risk priority number (RPN) with 175 is related to welding pliers (and heating of the handle due to loss of handle insulation) and drill (breaking the drill due to use Improper drill and high pressure to the machine) and the lowest risk priority number (RPN) with a value of 12 related to the millstone handle (wasting of the screw connecting the handle to the body due to lack of timely service). The results also showed that the risk priority factor various factors affecting the severity of the hazard, including: breaking the saw blade, burning the welding lathe and hitting the pliers by hand in the welding machine also had high relative priorities.

The results showed that based on the number of risks, a scheduled and regular schedule by labor inspectors and health centers and other related organizations to implement engineering control measures including control of chemical, physical,safety and ergonomic factors in the environment of welding workshops. Educate the employers of the workshops to get acquainted with the provisions of the labor law in welding and observe the mandatory laws, the need to use personal protective equipment, to be included in the list of strategic and practical programs.

Due to the importance of spiritual health in patients with thalassemia and its positive and significant effects on improving the treatment process and mental, psychological and social conditions of these patients and according to the results of previous studies, patients with thalassemia have high spiritual health. The lack of studies in this field, the present study was conducted to determine the spiritual health of adolescents with thalassemia major.

This descriptive-analytical study was performed on 100 adolescents with thalassemia major. Sampling was done by available means. Patients' spiritual health was measured using the Poltzin and Ellison spiritual health questionnaire. Data were analyzed using descriptive statistics tests and the relationship between mean spiritual health and mean age of patients with Pearson correlation coefficient test, its relationship with gender and place of residence with independent t-test and its relationship with economic status with ANOVA.

The mean and standard deviation of patients' spiritual health score was 74.23 ± 11.45, which showed a moderate level of spiritual health. 12% of patients (12 patients) reported low spiritual health, 84% (84 patients) reported moderate spiritual health and 4% (4 patients) reported high spiritual health.There was no significant relationship between spiritual health and demographic characteristics (p value > 0.05).

According to the results of this study which showed that adolescents with thalassemia have a moderate level of spiritual health and due to the high importance of spiritual health in improving treatment, adherence to treatment regimen, life expectancy and mental health of patients, It is necessary to take appropriate measures to improve the spiritual health of these patients.

In today's competitive environment, continuous, continuous and long-term relationship with the customer is the key to achieving the success of healthcare organizations. Therefore, this study was conducted to survey customer relationship management in affiliated hospitals of Zabol University of medical sciences.

This study is applied and descriptive in terms of method. The statistical population includes the staff of hospitals that 205 people were selected by simple random sampling method. The data collection tool was a two-part questionnaire (demographic and customer relationship management). Research data were analyzed using SPSS 18 software.

In this study, the average score of customer relationship management was 3.16 points. The average scores of each of the dimensions of attracting, maintaining and expanding customer relations, infrastructure dimension and customer orientation dimension were 3.1, 2.9 and 3.48 points, respectively.

According to the findings, customer relationship management and each of its dimensions was in a moderate position. Therefore, managers of health care organizations should take steps to improve each of the dimensions of customer relationship management in order to increase the loyalty of their customers and the productivity of the organization

This study was designed to investigate the effect of tranexamic acid and its side effects in preventing postpartum hemorrhage in patients referred to Ali ibn Abitaleb Hospital in Zahedanduring 2020-2021.

Patients were divided into two groups of 85 patients. Vital signs as well as drug side effects related to tranexamicity are monitored and recorded every 15 minutes in the first hour and every 30 minutes in the second hour. Also, blood samples are taken from patients to measure hemoglobin and hematocrit within 6 hours after delivery. The number and weight difference of droschitis used during 2 hours after delivery are also measured. In addition, PPH (Postpartum hemorrhage) cases in both groups were checked by repeated examination of the uterine fundus during the first 2 hours and after 6 weeks.

There was no statistically significant difference between the two groups in terms of the number of deliveries and further decrease in hemoglobin levels in the control group compared to the intervention group. Nausea, vomiting, and dizziness were observed in the intervention group and thrombosis was not observed in any group. According to the independent samples t-test, there was a statistically significant difference between the mean blood volume lost between the two groups. The mean hematocrit drop was statistically significant between the two groups. No blood transfusion was observed in any of the patients.

Tranxamicacid injections can effectively reduce postpartum hemorrhage and reduce maternal hemoglobin and hematocrit following this complication.

The PI3K/Akt/mTOR signaling pathway is one of the most important intracellular signaling pathways by regulating the cell cycle process. The direct relationship of this pathway with important mechanisms such as cell quiescence, longevity, and proliferation has been established. The overactive PI3K pathway with decreased and increased apoptosis and cell proliferation respectively is involved in pathogenesis of many cancers, including blood malignancies such as leukemia.

Laboratory findings have shown that different factors, such as miRNAs, play a role in regulating PI3K signaling pathway. These molecules can alter the fate of a cell by interfering in suppression/overexpression of mRNA, transcription factors or stimulating the transcription of some genes. In this article, we reviewed the role of miRNAs in regulating the PI3K/Akt/mTOR pathway and its effect on leukemic progression and treatment failure.

At present, miRNAs are known to be one of the causes of treatment failure and relapse in cancers.