Journal of Kermanshah University of Medical Sciences
Volume:16 Issue: 8, 2013

Formaldehyde (H2C = O)، is a member of aldehyde family with a simplest organic molecule، used in various industries. The aim of this experimental study was to investigate the effects of simultaneous formaldehyde and noise exposure on hormonal pituitary-gonadal axis in adult male mice. 46 adult male mice were randomly assigned to one control group and three experimental groups which were exposed to formaldehyde vapor (10 ppm) (F)، noise (100 dB) (N)، and simultaneous formaldehyde with noise (NF)، respectively for 10 days (8 hours a day). At the end of the experiment half of the mice of each group were sacrificed 24 hours after exposure (short-term effects) and the rest were sacrificed 35 days after the end of exposure (long-term effects). Plasma concentrations of testosterone، LH، FSH were measured using the ELISA method. In short-term analysis، the serum testosterone in groups N، F، and NF were 2. 73±0. 24، 2. 58±0. 16، and 2. 03±0. 22، (Ng/ml) respectively which had a significant decrease (p<0. 001) compared to control group (3. 82±0. 35). The LH level in groups F، and NF also showed significant reduction compared to control group (p<0. 05 and p<0. 001). Reduction of serum testosterone and LH level may be potentiated by noise (700-5700 HZ) in the simultaneous exposure to formaldehyde and noise.

For tissue engineering of bone، anatomical and operational reconstructions of damaged tissue seem to be vital. This is done via reconstruction of bone and appropriate biological joint with bone tissues of damaged areas. In this study the condition of biodegradable bed Nano fiber PHBV and USSC cells were used to accelerate bone repair of damaged area. Hollow nanofabrication scaffold of damageable life was designed as PHBV by electrocy and via determining the best factors such as the kind and amount of solvent، specific volume and rate. The separation of osseous tissue infiltration and evaluating its nature by flow cytometrocical analysis was done. Animal test including USSC as well as PHBV condition in the damaged bone was done in the rat. After 8 weeks the implanted area was analyzed using CT-scan and was sent to histopathology ward. Finally، the rate and quality of reconstruction were determined after H and E coloring. Histomorphic analysis indicated a statistically significant difference between the experimental group of PHBV، USSC+PHBV and control group. Besides، the histopathologic analysis showed that bone reconstruction rate was high in the area containing USSC and PHBV، compared with area having PHBV and control group and consequently the reconstruction quality of bones and the relationship between the new bone tissues and surrounding bone tissues were high too. Using PHBR scaffold and USSC together could be useful in the amending of wide range of bone lesion.

Leukaemia is a chronic disease with unknown cause whose treatment is included various stages such as bone marrow transplantation. Some research accredited the role of quality of life before transplantation in physical well-being after BMT. The purpose of the present research was to study the relation between quality of life dimensions and physical well-being of post-BMT in patients with acute leukaemia.

In this survey research، 58 patients with acute leukaemia (38 men and 20 women) between ages 18-45 years selected during 13 months via census procedure. Then، the subjects'' quality of life was assessed before BMT and their physical well-being were assessed one، two and three months after-BMT. Quality of life and physical well-being after BMT were assessed using SF-36 questionnaire and CBC test. Data was analyzed using univariate and regression analysis.

Results showed that some dimensions of quality of life (physical functioning، role limitations due to physical health، energy، social functioning and general health) can predict some dimensions of physical well-being after BMT in patients with acute leukaemia.

Attention to quality of life dimensions prior to BMT accompanying with other treatments appears to be critical for patients'' physical well-being after BMT.

Many adult smokers initiate the smoking habit during adolescence or as young adults. So prevention of cigarette use among adolescents has been recognized as an important public health priority around worldwide. The purpose of this study was to measure Theory of Planned Behavior (TPB) constructs regarding Cigarette use among the adolescents. This study was a cross-sectional one which was conducted on 215 adolescent (high school) students aged 14-19 in the city of Zarandieh. Data were gathered by a self-administered questionnaire that was constructed based on a literature review of research on smoking and on the TPB. Independent T-Test and logistic regression were employed to analyze the data. 14. 41% of the subjects were smokers. The TPB components (Attitude، subjective norms، outcome expectancies and perceived behavioral control) and variables like smoking friends، smoking family accounted for 42. 7% of the variance in intentions. Significant differences were detected between smokers and non-smokers regarding means of score of all the variables TPB (p<0. 001). The results indicate that the TPB is an effective model for predicting lifetime cigarette use among adolescents; these findings may contribute to the development of tailored interventions for the prevention of smoking among adolescents.

This paper aimed to study the relationship between spirituality، resiliency and coping strategies factors with students'' psychological well-being in Razi University of Kermanshah. The statistical population was Razi University students. The sample (N=375) were selected using stratified random sampling method. The information collection tools were demographic questionnaire، Ryff Psychology Well-Being Scale (RPWB)، Spirituality experience of Ghobari and et al، Conner and Davidson Resiliency Questionnaire (CD-RISC) and Coping strategies Scale of Lazarus and Folkman (WOCQ). This study was the correlation design and data were analyzed using stepwise regression. The results showed that variables such as: resiliency، spirituality، emotion-oriented and problem-oriented strategies predicted 60% of well-being variance (P<0/05). There was a positive relationship between resiliency، spirituality and problem-oriented strategy factors with well-being (P<0/05). However، there was not any significant relationship between emotion-oriented coping strategy and well-being. Since resiliency، spirituality and coping strategies variables are significant predictors of psychology well-being، the students psychological well-being will be enhanced by such capacities in educational settings.

Due to the increased growing heart diseases and necessity to do heart surgery، as well as the importance role of rehabilitation in reducing patient’s mortality، patient’s promotion body image and quality of life should be proposed as one of the main goals of treatment interference. This research was performed with the goal to identify the process of rehabilitation period on the changes of body image quality of life. In this descriptive –analytical research، 51 patient’s body image quality of life was reviewed in four time period (before، during، ending، and one month after the rehabilitation). Patients were selected based on available sampling. The tools of two parts questionnaire information collection include demographic information and Body Image Quality of Life questionnaire (BIQLI). The obtained information was analyzed using descriptive statistics and repeated measures ANOVA. In this research a statistically significant relationship was found between time and changes of body image quality of life and also between education level and body image quality of life (P less than 0/001). But no statistically significant relationship was found between age، sex، marital status، job، history of cigarette and opium consumption، history of underlying diseases and body mass index with body image quality of life. Due to the body image quality of life promotion in patients at the end of rehabilitation period، it is recommended that all heart surgery centers include implementation of rehabilitation programs and moderate of risk factors at the head of precautionary policies.

Cell culture is used in laboratory for variety of purposes. In addition، there are different cell harvesting methods. One of these methods is enzymatic method. In this method cells are separated from the plate via using enzyme such as Trypsin. This method، along with side effects of enzyme digestion effect، may affect other parts of cell. To avoid this، via using physical method cells would be separated from the plate. If this method be used it seems that، physical method could possibly damage survival of the cells. In this study، two kinds of damages were compared using Flow Cytometry. MKN45 gastric cancer cells were cultured in RPMI at 37 ºC and 5 %CO2 and after reaching to 80% density، they were separated from the plate using both physical and digestion methods. Then cell status was evaluated and analyzed using flow cytometry method. Results showed that cell death rate was higher using physical method than enzymatic method. This significant difference was confirmed by microscopic observations. Since using enzymatic method leads to low cell death rate، it seems that using this method is better than physical method for separation of cells from the plate.

Health workers ability to provide high quality care can be adversely affected by many factors such as sleep deprivation associated with shift work. The aim of this study was to compare sleep Disorders among shift workers and non-shift workers in Kermanshah Hospital (2005) At first، demographic information of the participants were gathered. 653 Volunteers were divided into two groups of shift workers and non-shift workers based on age، gender، marital status and education. The participants completed the Global sleep Assessment Questionnaire for sleep problems. Then data were analyzed using z –test and x 2، Shift workers suffered from daily sleeping (p=0/001)، daily dysfunction due to sleepiness (p=0/001)، insufficient sleep (p=0/001) and sleep apnoea (p=0/001) as compared with non-shift workers significantly. This study showed that there is a significant relation between shift work and sleep problem regarding daily sleepiness and apnoea and shift working. These problems can affect clinical performance and may be an important factor in patient safety and health worker''s well-being.

Ongoing measurement of quality of life especially in patients with chronic diseases، maybe the basis of health care evaluation. This study aimed to assess and identify factors affecting quality of life in hemodialysis patients in Kermanshah city.

This is a cross sectional study carried on 98 cases of hemodialysis patients referred to two of teaching hospitals (Imam Khomeini and Imam Reza affiliated to Kermanshah University of Medical Sciences. Available sampling applied to patients who started dialysis at least three months before. Demographic data collected and SF-36 questionnaire of quality of life performed which its validity and reliability has been confirmed previously in Iran.

The physical health score decreased with increasing age (P<0. 05) and increased with increasing education level (P<0. 005). In addition، physical health in those who did not exercise any time were less than the other (P<0. 001). Overall mental health scores increased with increasing education level (P<0. 001) and increasing household income was associated with increasing mental health score (P<0. 05). The overall score of mental health for those who had always exercised was more than the others and for those who did not exercise any time was less than (P<0. 001). The overall score of mental health in people who had dialysis twice a week was the highest (P<0. 05).

Considering the impact of physical activity and socioeconomic status on patients'' quality of life accounting، these factors in order to promoting the quality of life will be effective.

Anxiety disorders and substance abuse are commonest comorbidities among Bipolar I Disorder (BID) patients. This study investigated the prevalence of anxiety disorders among BID patients based on their dependency on opioid. In this cross sectional study the BID patients in Iranian hospital of psychiatry were divided into two 89-patient groups; one group was considered as opioid dependent and the other as non-dependent. Then clinical characteristics and prevalence of anxiety disorders were inspected by demographic and clinical questionnaire، the Structured Clinical Interview for DSM-IV axis I disorders (Persian version)، Hamilton Rating Scale for Depression and Young Rating Scale for Mania. The collected data were analyzed using T-test، Chi square and logistic regression. Among anxiety disorders، only panic disorder was significantly different between two groups of BID patients There is a different correlation between opioid dependency and comorbidity of various types of anxiety disorders in BID patients.

The benign mesothelioma is a rare tumor with unknown etiology and its common symptoms are abdominal pain، mass and ascites. Diagnosis is problematic and laboratory findings aren’t specific. The selected treatment is removing the mass completely by surgery. The case was a 32 years old woman who، following diagnosis of primary infertility cause and without any other biological symptoms after MRI with probable diagnosis of hydatid cysts or multiple abdominal cysts was undertaken laparotomy. In the laparotomy، different serocyst adenoma with various sizes that was developed from in the half right of pelvic up to liver edge was observed and removed thereafter. The study confirmed the benign histopathologic mesothelioma. The benign mesothelioma should be taken into account in the diagnosis of pelvic cystic masses including hydatid cyst.

Cerebral venous thrombosis is a rare but dangerous complication that occurs more often in young adults. This study aimed to determine the demographic characteristics، the predisposed population، the underlying causes and paraclinical findings in patients with cerebral venous thrombosis in Kermanshah city. In this case study the patients'' files in six hospitals during 6 years، from 2002 to 2008 were addressed. Approximately 75% of patients were females aged 40. 2 + 17. 22 years. Most visitors were preceded in December and February. Superior Sagittal sinus was the most common location for cerebral venous thrombosis. Tomography scan was reported normal in 47. 5%.

Proper nutrition plays an important role in physical and cognitive development of children. The early diagnosis and treatment of eating problems is very important. This study aimed to survey eating problems of children with Down syndrome. In this descriptive-analytic study، an eating problem test used to survey eating problems of children with Down syndrome in exceptional schools. The findings of the study indicated a high prevalence of eating problems in children with Down syndrome. Difficulty in eating skills such as chewing and swallowing in these children were more prevalent (80%). Exact assessment of eating problems of children is very important