Comparison between Serum Vitamin D Level in Children with Type I Diabetes Mellitus and Non Diabetic Children

Vitamin D is the only vitamin that acts as a hormone and its deficiency impairs insulin synthesis and excretion. This study aimed at evaluating the serum vitamin D level in children with type 1 diabetes mellitus and its correlation with HbA1C. In this analytical study، serum vitamin D level in 50 type I diabetic children was compared with that in 50 healthy subjects. In diabetic group، correlation between serum vitamin D level and HbA1C was evaluated as well. The median serum 25 (OH) D3 level in diabetic group was significantly lower than that in the non-diabetic group (31. 05 mmol/L vs. 42 mmmol/L، P=0. 01). In the diabetic group، there were 19 cases (38%) with deficient and 31 cases (62%) with insufficient serum level of 25 (OH) D3، while in the non-diabetic group، there were 9 cases (18%) with deficient and 41 cases (82%) with insufficient serum level of 25 (OH) D3 (P=0. 03). There was no significant correlation between serum level of 25 (OH) D3 and HbA1c (P=0. 7، r=0. 06). Children with type I diabetes mellitus had low serum vitamin D level in comparison with non-diabetic healthy children. There was no significant correlation between serum vitamin D level and HbA1C.