Optimal Dose of Contrast agent Concentration, Using Spin Echo and Inversion Recovery T1-Weighted Sequences during MRI

It is important to know how much contrast agent should be used to receive the maximum signal intensity (SI). The aim of this study was to investigate the optimal doses، which maximize the SI in the Hypophysis region on T1-weighted image; using spin echo and inversion recovery sequences. After injection of 15ml of contrast for all patients with different body surface area (BSA)، spin echo and inversion recovery T1-weighted images was obtained. All studies were carried out using a 0. 3 (Tesla) clinical MR scanner. Mean SI was obtained in the Hypophysis region. The result shows that injections of 15cc of radio contrast create higher SI of the Hypophysis region in those with lower BSA. While in those with higher BSA this routine dose leads to low concentration in the region of interest and lower SI will be detected. Using a fix dose of radio contrast lead to a decrease in the maximum SI and it should be adjusted based on the patients BSA.