Survey of clinical manifestations in Henoch Schönlein purpura in follow up

Henoch Schönlein purpura (HSP) is a small vessel leukocytoclastic vasculitis that generally occurs in children, and 90 percent of cases are under 20 years old. The aim of this study was to examine the clinical manifestation in follow-up of Iranian children affected with Henoch Schönlein purpura (HSP). In a case study during 2012, 155 children with a diagnosis of HSP treated in children’s medical center hospital from September 2008 to September 2011 were included. All patients were re-examined for new symptoms as well as complications. the most cases of HSP aged among 3 and 6 yaers old and it was slightly more frequent in boys. At onset, the most common presenting symptoms, were purpura (85.5%), gastrointestinal manifetations (61.9%) articular involvement (61.3%), and in the course of disease were purpura (96.1%), constitutional symptoms (84.5%) and articular involvement (74.2%). Based on the follow-up conducted in 2012, a statistically significant correlation was observed only in renal complications and increasing age of patients (P=0.007) Because renal failure is a major complication of HSP, it is recommended that all patients with proteinuria in the acute phase, have a blood pressure examination and urine-analysis once a year.