Evaluation of cutoff point and power of neutrophil to lymphocyte ratio in diagnosing chronic inflammation in End-stage renal disease (ESDR) patients

Inflammation can increase mortality and morbidity rate of ESRD patients. In some studies Neutrophil to lymphocyte ratio and Platelet to lymphocyte ratio were evaluated to detect inflammation. This study was conducted to evaluate the deterministic power، specificity and sensitivity of Neutrophil to lymphocyte ratio and Platelet and lymphocyte ratio in detecting inflammation indicated by Serum Albumin and C-reactive protein (CRP). According to our inclusion and exclusion criteria، we recruited 120 patient with ESRD admitted to Loghman hospital and Ashrafi Esfehani hospital were examined retrospectively in our study. Data were collected from hospital documents. Basis on our study، Neutrophil to lymphocyte ratio and Platelet and lymphocyte ratio didn’t show a significant difference between normal patients and patients with inflammation. Although Neutrophil to lymphocyte ratio and Platelet and lymphocyte ratio are related to inflammatory conditions، but sensitivity and specificity of these testes are low for detecting inflammation.