The Relationship Between Pre Procedural Glucose and Contrast Induced Nephropathy in the Patients with Acute Coronary Syndrome Undergoing Coronary Angiography

Contrast Induced- Acute Kidney Injury (CI-AKI) is a common complication of coronary angiography. Contrast material may cause kidney damage, including oxidative stress, free radical damage and endothelial dysfunction. All of these processes in the context of hyperglycemia also rumored to be enabled. It is therefore possible that the combination of hyperglycemia before the procedure and exposure to contrast agent during coronary angiography dramatically increases the risk of CI-AKI. Stady of The Relationship Between Pre Procedural Glucose and Contrast Induced Nephropathy in the Patients with Acute Coronary Syndrome Undergoing Coronary Angiography. All patients who were hospitalized with a diagnosis of acute coronary syndrome and coronary angiography were enrolled. Serum creatinine and blood sugar along with other routine tests in the acute phase, when the patient is admitted to hospital, were recorded. 24 hours and 7 days after angiography creatinine level was measured again. Multivariate analysis predictors of blood sugar level before angiography and contrast induced nephropathy after angiography and disease control confounding variables, logistic regression in final model showed that in diabetic patient blood sugar level before angiography (p= 0/032), is a predictor of contrast induced nephropathy. Raise of blood sugar before angiography is a predictor of contrast induced nephropathy after angiography in diabetic subjects. Prophylaxis to prevent CI-AKI then close renal monitoring after procedure are recommended.