Histologic and histomorphometric study of epididymis after immobilization stress in mice

Immobilization stress as a physical and psychological stress, has adverse effects on various body tissues. Numerous studies have been conducted on the effects of stress on reproductive system and fertility. The Main aim of this study is evaluation of effect of immobilization stress on epididymal tissue in mice. In this study 140 adult male mice were randomly divided in to 7 groups as test and 7 groups as control animals. In test groups,the animals were subjected to immobilizationstress for 1, 3, 7, 15, 30 and 60 days respectively. In control groups,the animals were only handled. After the experimental periods, blood samples were collected for measurements of serum cortisol and testosterone and epididymal tissue samples were obtained for histologic and histomorphometric study. The results of this study showed that level of testostrone in all test groups significantly decreased in comparison tothe control groups(p