The effect of vitamin D supplementation on blood pressure in prediabetic adults: a randomized clinical trial
Message:
Abstract:
Background and Aims
Vitamin D plays several important roles in human body. Studies showed that low serum 25(OH) D results in hyperglycemia, hypertension and cardiovascular disease. The objective of current study was to examine the effect of 3-month supplementation with 1000IU vitamin D on blood pressure in prediabetic adults.
Materials and Methods
In a 3 month randomized clinical trial, 120 eligible subjects were randomly assigned to vitamin D or placebo group; they were stratified according to percentage of body fat mass in four blocks to receive 1000 IU/daily vitamin D or an identical placebo tablet for 3 months, respectively. Participants were adults aged 18-70 years old with prediabetes. Systolic blood pressure (SBP), diastolic blood pressure (DBP), serum 25(OH)D levels, BMI, waste circumference, percentage of body fat mass (FM), physical activity, sun exposure, energy and macro nutrient intake were assessed before and after the intervention.
Results
In the intervention group serum levels of 25(OH) D increased significantly (from19.36 to 30.48, P
Conclusion
The daily supplementation of 1000IU vitamin D for 3 months has no effect on the blood pressure.
Language:
Persian
Published:
Urmia Medical Journal, Volume:27 Issue:11, 2017
Pages:
1003 - 1011
magiran.com/p1654800  
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