Effects of Exposure to WI-FI Signals (2.45 GHz) on Serum Oxidative Stress and Single Strand DNA Breaks in Peripheral Blood Lymphocytes of Mice

Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Introduction
Use of wireless devices have been increasing during the last three decades in the world. Health risks caused by exposure to these appliances has become a public concern. The purpose of this study was to investigate the effects of exposure to Wi-Fi on DNA breaks and oxidative stress parameters.
Methods
16 male mice divided in 2 groups; experimental (exposed) (n=8) and the control groups (n=8). While the control group was kept not exposed to the signals the experimental group was exposed to 2.45 GHz Wi-Fi signal GHz, for 8h/21 day; Single strand DNA breaks in lymphocytes were determined by using the Alkaline Comet Assay (before and after the exposure period). Oxidative stress parameters, including, catalase activity, PON1 activity, and TAC were measured (before and after the exposure period).
Results
In the exposed group, it was observed an increase in single-stranded DNA break; decrease in PON1 enzyme activity also increase the catalase activity compared to before exposure to wi-fi, but TAC was not significantly different. While in the control group, none of the indicators measured at the end of the study there was no significant difference compared to 21 days ago.
Conclusion
The findings of the present study show that Wi-Fi exposure can increase oxidative stress and the strand DNA breaks
Language:
Persian
Published:
Journal of Shaeed Sdoughi University of Medical Sciences Yazd, Volume:25 Issue: 7, 2017
Pages:
572 to 584
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