The effect of oral administration of Folus (Cassia fistula( fruit aqueous extract on abomasal emptying rate in neonatal lambs

Abomasal hypomotility plays an important role in pathogenesis of some abomasal disorders such as abomasal bloat that there are same serious side effects associated with using synthetic drugs for its treatment, such as diarrhea and antibiotic resistance and for decreasing these side effects, administration of herbal medicine can be appropriate approach. Evaluating effect of Folus fruit aqueous extract on lamb,s abomasal emptying is goal of this study. This study was conducted on twelve five-day-olds Sangsari-female-lamb (average weight 4 kg). lambs received five oral treatments including salin (30ml), Eeythromycin (400 mg), Folus (700 mg/kg), Folus (750 mg/kg) and Folus (800 mg/kg), respectively Acetaminophen absorption test was used to evaluating the rate of abomasal emptying. After drawing relational model between plasma Acetaminophen concentration and time with regression method showed that treating with erythromycin and three different doses of aqueous extract of Folus fruit (700, 750, 800 mg/kg) increased the rate of abomasal emptying in comparison to the negative control, significantly (P<0.05). No clinical side effects were observed following the administration of erythromycin and Folus in lambs. This study showed that aqueous extract of Folus fruit has a stimulatory effect on lamb's abomasal emptying but more studies are needed on the effect of this plant components on abomasal emptying.