The relationship between HbA1c and microalbuminuria in type II diabetic patients in Isfahan province

The increase in kidney disease is partly due to an increase in the prevalence of diabetes. Type 2 diabetes often occurs in adults.. The aim of this study was to investigate the relationship between HbA1c   and microalbuminuria in type II diabetic patients in Isfahan province by biochemical methods.

In this study, 50 patients with type II diabetes and 50 healthy subjects were blood samples. Also, microalbumin was collected from both groups of 24-hour urine samples. Then, HbA1c   was measured by HPLC method and the microalbumin content of the specimen was measured by Immunoturbidimetric method. Data analysis was done using SPSS software. Comparison of quantitative data was performed using T-test, qualitative data with A, qualitative data with Chi-square test and U Mann Whiteny test.

The results indicate that with increasing levels of HbA1c  , the rate of microalbumin release also increases in type II diabetic patients. Biochemical indices such as FBS, BUN, Cr, U.Acid, potassium, serum albumin were significantly higher in the control group than in the control group.

According to the results obtained from this study, it can be concluded that type 2 diabetes mellitus causes an imbalance in the excretion of microalbumin from the kidney. Also, the study of HbA1c   is a useful parameter in the evaluation of type 2 diabetes.