A Review of 20 Years of Lipidomics; Applications and Tools

"Lipidomics" as a new branch of wider science "Omics"; recently taken into consideration. Although this science was ignored in the past decades, due to its role in creating a deeper understanding of systems biology and biochemistry knowledge recently has been considered as a promising research field having compared with other omics sciences. The present study first introduces the science lipidomics and its delimitation, then discusses its varied applications in various industries like: medical science, pharmaceutical, feed and biofuel industries. Tools and methods to identify and process the lipids contains methods based on mass spectrometry, spectroscopy and chromatography, chemical and imaging techniques, have contributed to the development of lipidomics; this collection with in silico tools, bioinformatics and databases have become explained. Developing areas of science lipidomics have resulted in expansion of applied research in the field of quantity and quality improvement of bio-oils, identification of disease symptoms and biomarkers related to lipidome. Moreover it could end to exploration of different pathways and enzymes involved in fat metabolism in the future.