The effect of Gender on p53 Levels After Downhill Running in Non-Athletes

The effect of gender on related-exercise apoptosis is unclear.The aim of this study was to investigate the effect of gender on the p53 level, as apoptosis marker, after downhill running in non-athletes.

Eighteen individuals between the ages of 18 and 30 years were randomly selected and divided into 9 groups (9 males and 9 females). Subjects performed downhill running (12% incline) at 70% of HRmax for 40 min and blood samples were taken before exercise and immidatly after exercise. Blood samples were assayed for serum level of p53.

The results showed that p53 was significantly increased after running downhill compared to pre-test in both male and female groups, but this increase was not significantly different between the two groups of men and women.

Although more research is needed, we showed that gender was not found to play an important role in apoptosis response to downhill running in non-athletes.