Effect of Hydroalcoholic Essence of Psydium guava on Blood Cells in Male Rats

Application of plants and their compounds has long been significant in treating diseases mainly due to their natural potential and lower side effects than chemical drugs and presence of alkaloids, and polyphenols in their extract. Despite research carried out on the properties of such plants and popularity of blood diseases, few studies have been done on its effects on blood cells, thus, it was attempted for the first time to evaluate the effect of hydroalcoholic extract of the Pseudium guava leaf on blood cells in rats.

After extracting the leaves of guava plant, 40 adult male rats were divided into four groups. Which included control (cases with no treatment during the study) and experimental groups (cases receivied of hydroalcoholic extract of Psidium guava leaf, in different doses daily for 3 months). At the end of the test period, blood samples were counted.

The results of this study showed that the hydroalcoholic extract increased White Blood Cells and Red Blood Cells, but no significant change was observed. This increase in hematocrit was significant in the group receiving hydroalcoholic extract at a dose of 5000 mg/kg compared to the control group.

The results of the study had a positive effect on blood cells. Also, the lack of cytotoxicity with high doses of the extract of this plant means its safe use in traditional medicine.