Efficacy of Saffron Petal by-Product in Treatment of Burn Wounds in Male Rats

Natural and herbal ingredients have long been used to treat burns. Care, treatment and rehabilitation in burns, as a challenge, poses huge costs on people, family and health system. The current study aimed at assessment of saffron petal extract in the treatment of heat-induced burn wounds in rats.  

The ethanol extract of saffron petal was examined on 24 Wistar rats in four groups including control, SSD 1%, saffron 8%, and saffron 5%. Burns were created on the back of all rats according to the standard method. During 21 days, the average wound size in all groups was recorded daily.

The highest healing effect was observed in 5%, 8% saffron, SSD 1% ointment and control groups, respectively. Furthermore, no burning scar was observed in saffron groups.

The saffron petal extract at a dose of 5% showed a significant effect on the healing of second degree burn wounds in rats. Further complementary studies on other extracts and doses are recommended.