The Effect of 30-Hours Sleep Deprivation on the Response of Leptin and Ghrelin Levels to an Exhaustive Activity Among Active Male Students

Sleep deprivation is one of those factors that affect the energy intake and appetite of individuals. It is reported that sleep deprivation affected by certain hormones (e.g. insulin, Leptin, ghrelin, and cholecystokinin, etc.) that are involved in energy balance may affect body weight through appetite. The purpose of this study was to investigate the effect of 30-hours sleep deprivation on the response of leptin and ghrelin levels to an Exhaustive activity among active male students.

Among the active male students of Razi University of Kermanshah, 20 undergraduate students were selected through convenience sampling and participated in the study. Subjects were evaluated by simple randomized cross-sectional design in two situations.

Information related to the comparison of post-test and pre-test in two experimental (sleep deprivation) and control (adequate sleep) situations showed that leptin hormone in sleep deprivation conditions decreased compared to rest conditions (9.4 %) And ghrelin hormone in experimental conditions increased compared to control conditions (2.04%) and this difference is considered significant at the level (p = 0.0012). Insomnia also caused significant changes in physiological parameters (VO2max, heart rate, blood pressure, time to exhaustion, etc.).

30 hours of sleep deprivation decreased leptin and at the same time increased ghrelin, which indicates the importance of night sleep, which is one of the influential factors associated with obesity and overweight.