Evaluation of the Effects of Anvillea garcinii Extract and Exercise on Sex Hormones in Male Rats with Hyperlipidemia

The aim of this study was to evaluate the effect of exercise and Anvillea garcinii extract on sex hormones in male rats with hyperlipidemia.

35 male wistar rats randomly divided into five groups (n=7 for each group), including: 1) control group (Con), 2) hypercholesterolemia (Hc), 3) Anvillea garcinii extract (Ext; 100 mg / kg), 4) training group (E), 5) Extract-exercise (E-Ext). Exercise was performed for eight weeks, 30 minutes and three sessions per week equivalent to a speed of 14-17 m / min.  Levels of testosterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH) and prolactin were measured by radioimmunoassay and hormone kits. ANOVA test was used to determine the differences between groups.

The results showed a significant difference between the levels of FSH, LH, Prolactin and Testosterone between the groups. The results of Tukey post hoc test showed that FSH, LH and Testosterone levels between E-Ext and Hc groups (p = 0.000) (p = 0.001) (p = 0.001), Ext (p = 0.000) (P = 0.000) (p = 0.008) and E (p = 0.000) (p = 0.011) (p = 0.015) and Prolactin level between E-Ext groups with Hc (0.015). There was a significant difference between Ext (p = 0.046) and E (p = 0.012). The results showed all sexual hormones except Prolactin increased in the E-Ext group compared to the Hc group.

Consumption of plant extracts along with exercise can have positive effects on sex hormones.