The Investigate of Effect Eight Weeks of Combined Exercise on P3NP, CAF and IGF-1 on CABG Patients

This study aimed to investigate the effect of eight weeks of combined exercise on P3NP, CAF and some sarcomopia factors in CABG patients.

24 CABG middle-aged men participated in this study. Then the participants were randomly divided into two groups of 12-person combination exercise (mean age 54.58 ±6.47 years) and control group (mean age 50.70 ±7.70 years). Anthropometric indices and serum P3NP, CAF and IGF-1 blood parameters were prepared and analyzed before and after training. The eight-week combined exercise program was conducted in three sessions with the supervision of cardiac rehabilitation specialists. Repeated measures statistical test was used for data analysis.

Combined exercise was associated with a significant decrease in serum P3NP levels (p=0.001), but these changes were not significant compared to the control group (p=0.334). But these changes were not significant compared to the control group (p=0.334). There was also a significant increase in serum CAF levels in the post-test compared to the pre-test (p=0.02) and the differences between the control group and the training group were significant (p=0.038). On the other hand, a significant increase in serum IGF-1 levels was observed in the post-test compared to the pre-test (p=0.001), but the serum levels of IGF-1 were not significant in the control group (p=0.280).

A short-term combination training in CABG patients increased IGF-1 and CAF, but no change in P3NF levels. Further research is needed to investigate the effect of combined exercise on CAGB patients on these indices.