The effect of eight weeks of increasing training with marjoram supplementation on muscle inflammatory indices in healthy rats

Muscle inflammation or myositis is a general description of chronic and progressive inflammation involving muscles. The aim of this study was to investigate the effect of eight weeks of increased training with marjoram supplementation on muscle inflammatory indices in healthy rats.

In this study, 27 rats of about two months (200-250 g) were randomly divided into three groups: control, endurance training and endurance training + marjoram. They got rat were kept in groups of 9 in conditions of free access to water and food. The treadmill endurance training program was performed for eight weeks, five days a week, without slope, and for the first to third week of each session for 40 minutes, and in the eighth week for 60 minutes. Marjoram supplement was given to the rat in the supplement group using a mixture of water. Findings were analyzed spss at the significance level (p = 0.05).

The results showed that there was a significant difference between the three groups in the amount of TNFα, IL-6, CK. The results of Tukey post hoc test showed that the rate of inflammatory markers after exercise without supplementation increased significantly, which was significantly lower in the endurance + marjoram group than the control group. Also, the results showed that there was a difference between the endurance and endurance training groups with marjoram and the control group.

Increased endurance training with marjoram consumption probably increases the total oxidative capacity.