The Effect of 8 Weeks Sodium Alginate Supplementation and High Intensity Interval Training on Lipid Profiles and Liver Enzymes in Metabolic Syndrome Women

The prevalence of obesity is recognized as a health problem worldwide. Metabolic syndrome as the most important obesity factor is considered as one of the health problems in all societies. Supportive and complementary interventions are considered improvements in the status of individuals with metabolic syndrome. Therefore, the aim of this study was to investigate the effects of eight weeks of sodium alginate supplementation and high intensity interval training on lipid profiles and liver enzymes in metabolic syndrome women.

Thirty women with metabolic syndrome were randomly assigned into 4 groups: intermittent exercise (High Intensity Interval Training)+supplement (n=9), intermittent exercise (HIIT) )n=8), complementary (n=7) and control group (n=6). Subjects in HIIT and HIIT + supplementation groups performed three sessions of intermittent exercise each week for eight weeks with an intensity of 85% to 95% of the maximum heart rate. Sodium alginate supplementation was taken three times a week and 30 minutes before meals in the amount of 1.5 g of sodium alginate dissolved in 100 mg of water. Blood sampling were taken from all 4 groups 48 hours before and after the exercise program. One-way ANOVA and t-test were used for data analysis (P≤0.05).

The results showed that in the exercise+supplement group lipid profile (P=0.005) and aspartate aminotransferase (P=0.012)(17.8%), fat percentage (P=0.001)(9.7%), BMI (P=0.000) and alanine aminotransferase (P=0.035)(12.7%) compared to the other group were significantly reduced, indicating the effect of intermittent exercise and supplementation on improving the symptoms of metabolic syndrome in women participating in this study.

According to the results of this study, it seems that high intensity intermittent exercise with sodium alginate supplementation can be effective in prevention of some obesity related diseases and treatment of the metabolic syndrome.