The effect of three different exercise methods HIIT, HIT and MIT on the expression of FGF and TGF genes in liver tissue of male Wistar rats

The aim of this study was to investigate the effect of different exercises on the expression of FGF and TGF genes in the liver tissue of male Wistar rats.

For this purpose, 32 Male Wistar rats with an average weight of 250 g were prepared. Mice randomly divided into four equal groups of control, moderate intensity training, and high intensity training and high intensity intermittent training. The training groups participated in moderate-intensity, high-intensity, and high-intensity interval training programs for 8 weeks. 24 hours after the last training session, rat liver tissue was extracted and stored at -80 ° C and the amount of TGF and FGF gene changes was determined using Real time PCR. One-way analysis of variance and Tukey's post hoc test used to examine the differences between groups of variables. SPSS-24 used for data analysis.

 The results showed that there was a significant difference in the expression of TGF and FGF between the groups (control, HIT, HIIT and MIT) (p = 0.0005) (p = 0.001).The results of Tukey test showed that there was a significant increase in TGF gene expression among training groups (HIT, MIT, HIIT) compared to the control group (P = 0.001)In addition,  There was also a significant increase in FGF gene expression among training groups (HIT, MIT, HIIT) compared to the control group (P = 0.001).

In the present study, it was shown that three training methods, MIT, HIT and HIIT, increase the expression of TGF and FGF in liver tissue, but it seems that the expression of these genes in MIT training was more than HIT and HIIT.