The effect of endurance training on lipid oxidation level and antioxidant capacity of whole testicular tissue in cadmium-induced infertility in adult male rats

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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background and Objectives

induces lipid peroxidation, increases malondialdehyde, and decreases total oxidative capacity in the testis by producing free radicals. Resulting in damage to the intracellular defense system and infertility the aim of this study was to determine the effect of a period of aerobic exercise on malondialdehyde levels and total oxidative capacity of testicular tissue in cadmium chloride-induced infertility in adult male rats.

methods

In this experimental study, 32 adult and healthy male Wistar rats weighing 250 ± 30 g and aged 12 weeks were used.  Which was randomly divided into four groups of eight as follows: Intact group (Int) (I) 2- Exercise group (E), 3- Cadmium chloride group (C) 4- Cadmium exercise group (CE). Aerobic exercises were performed 5 sessions per week for 5 weeks. Data were analyzed using one-way analysis of variance and LSD post hoc test at a significance level of 0.05.

Results

Endurance training in this study has led to an increase in MDA and TAC (P /0.05) The results of the present study show Moderate-intensity endurance training was associated with a significant increase in total oxidative capacity of testicular tissue in cadmium-induced infertility. Cadmium also increases oxidative stress markers and decreases antioxidant enzymes. On the other hand, moderate intensity endurance training is associated with a significant increase in antioxidant enzymes

Conclusion

According to aerobic exercise in infertile mice cadmium can be mentioned Regular moderate-intensity exercise has made the body more resistant to oxidative stress.

Language:
Persian
Published:
Qom University of Medical Sciences Journal, Volume:16 Issue: 4, 2022
Pages:
330 to 341
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